US National Toxicology Program: more focus on human-relevant non-animal approaches for safety testing
The focus was on using approaches more relevant to humans when studying chemicals.
To protect public health, animal studies have been effective at identifying chemicals that may cause human harm, but that protection has come at a significant price. Many researchers are reluctant to use animals in ways that intentionally cause harm. They also face the challenge of extrapolating effects in animals to potential effects in people.