
European scientists continue to support an EU roadmap to accelerate the transition to non-animal science
The transition to non-animal science can offer more effective and accurate humane solutions for biomedical research and regulatory testing, and has been acknowledged by the European Commission, EU agencies, the cosmetics, chemical, pharmaceutical and healthcare industries, the consumer goods sector, and academia as an important step in tackling the health and environmental issues that threaten society today. This transition is overwhelmingly supported by Members of the European Parliament and EU citizens, and is in line with the European Union’s objective to fully replace the use of animals in science.
To achieve improved human health and environmental protection, it is essential to coordinate EU efforts and policies that facilitate and prioritise the transition to non-animal science in all EU research, innovation and education initiatives. Clear short-, medium-, and long-term actions are needed to guide and accelerate the adoption of innovative non-animal approaches while phasing-out animal-based methods. In addition, a coordinated European Research Area (ERA) initiative can revolutionise the scientific landscape by supporting innovation, research infrastructure, and knowledge sharing to train and inspire scientists, educators, students and regulators in the use of non-animal approaches.
The undersigned call on the European Commission and the Member States to establish an EU roadmap and launch an ERA action. This initiative should include concrete milestones, cross-sector support, open science principles, dedicated funding and harmonised education and training initiatives to accelerate the transition to non-animal research, regulatory testing and education.
If you are an EU academic or scientist and wish to sign this open letter, please follow this link.
Name |
Position |
Affiliation |
Country |
Comment |
Martin Paparella |
Senior Researcher |
Medical University Innsbruck |
Austria |
|
Bernard GODELLE |
University professor |
University of Montpellier |
France |
|
Penny Nymark |
Assistant Professor |
Karolinska Institutet |
Sweden |
In parallel with development of non-animal methods, known as New Approach Methodologies (NAMs) within chemical risk assessment, it is also paramount that all generated data in science is made Findable, Accessible, Interoperable and Reusable (FAIR)! Besides being a non-animal method in itself, reuse of data is the only way we can move into an era of machine-driven and AI-supported predictive chemical risk assessment without the reliance on animal testing. |
Pranjul Shah |
Head of the Incubator |
University of Luxembourg |
Luxembourg |
|
Mario Rothbauer |
Group Leader |
Medical University of Vienna - Dpt. Ortho Trauma Surgery |
Austria |
|
Dania Movia |
Assistant Professor |
Trinity College Dublin |
Republic of Ireland |
|
Prof. Dr. Stefan Dübel |
Head, Dept. of Biotechnology |
Technische Universität Braunschweig |
Germany |
|
Ashwani Sharma |
Co-founder |
Insight Biosolutions |
France |
Hello, I agree that we need alternative methods than animal testing as using like human in vitro models can give better results than animal testing. |
Janneke Hogervorst, PhD |
Postdoctoral researcher |
Hasselt University |
Belgium |
For many areas of research, animal testing is known to have very limited validity. We don't need to first develop non-animal methods there; we should just end animal experiments there right now and spend our limited resources on other research. We need more systematic reviews into the validity of animal experiments, rather than treat animal experiments as the gold standard that we need to find replacements for. Ending what doesn't work is innovation too. |
Love Hansell |
PhD Researcher |
Radboud University |
Sweden |
|
Bas van Balkom |
Asst Professor |
UMC Utrecht |
The Netherlands |
|
Margherita Scarpa |
Engeneer |
Institut Jacques Monod |
France |
|
Federica Emiliani |
Lecturer |
InHolland University of Applied Sciences |
The Netherlands |
Investing even more in in vitro/silico modelling |
Birgit Goversen |
Postdoctoral researcher |
Amsterdam UMC |
The Netherlands |
- More funds for the improvement of current NAMs - A focus on understanding, supporting and convincing stakeholders; not on forcing them to use NAMs |
Merel Ritskes-Hoitinga |
Prof. in Evidence-Based Transition to Animal-Free Innovations |
Utrecht University |
The Netherlands |
Setting goals is key, just like we do for the economy. The science and technology ARE here to move to non-animal science. By teaming up with social sciences and key stakeholders we can accelerate and strive towards ending animal testing by 2035. |
Rosalinde Masereeuw |
Full professor |
Utrecht University |
The Netherlands |
Make sure everybody is on-board, we can only make the transition together. |
Mathieu Vinken |
ONTOX coordinator/university professor |
Vrije Universiteit Brussel |
Belgium |
|
Koen Kramer |
Researcher animal ethics |
Wageningen University & Research |
The Netherlands |
|
AC van Veen |
Postdoc |
Radboud University |
The Netherlands |
|
Tuula Heinonen |
Professor |
Tampere University |
Finland |
Regulators give acceptance criteria for approving non-animal methods to predict safety (all chemicals) for all end points and efficacy (drugs) |
Julia D Zajac |
Project manager |
Vrije Universiteit Brussel |
Belgium |
|
Sonja von Aulock |
Editor in chief, CEO |
ALTEX - Alternatives to Animal Experimentation |
Germany |
|
Tobias Theska |
PhD Student |
Max Planck Institute for Biology Tübingen |
Germany |
|
Ingeborg Eva Reihs |
Doctoral candidate |
Medical University of Vienna |
Austria |
More specific funding for absolute animal-free and clean science, method establishment. Awards for absolute animal-free approaches and more critical thinking about so-called animal-free research. |
Alicia Paini |
Senior Toxicologist |
esqLABS GmbH |
Italy |
|
Eliska Kuchovska |
postdoctoral researcher |
IUF - Leibniz Research Institute for Environmental Medicine |
Germany |
|
Marina Garcia de Lomana |
Research Scientist |
Bayer AG |
Germany |
|
Job Berkhout |
PhD Student |
UU, RIVM |
The Netherlands |
|
Domenico Gadaleta |
Scientific Consultant |
Istituto di Ricerche Farmacologiche Mario Negri - IRCCS |
Italy |
|
Katharina Koch |
Postdoctoral Researcher |
IUF - Leibniz-Research Institute for Environmental Medicine |
Germany |
More interaction between researchers, the regulatory bodies and the industry. ECHA for example! More case studies supported by the regulatory bodies and indurtry. More guidance on the use of PBTK in POD estimation. |
Erwin L Roggen |
CEO and WP6 leader of the ONTOX project |
3Rs Management and Consulting ApS |
Denmark |
Willingness to change and courage to embrace innovation in practice, not only words. |
Ellen Fritsche |
Professor |
DNTOX GmbH |
Germany |
Establish case studies involving different stakeholders and compare classical risk assessment to NAM-based risk assessment. |
Helena Kandarova |
ESTIV President, Director of UEFT CEM SAS |
ESTIV and Slovak Academy of Science |
Slovakia |
Please try to harmonize legistlation accorst various sectors so that animal testing is not requested in areas, where replacements are availabe (e.g. medical devices, pesticides, pharmaceuticals) |
Alessio Gamba |
Postdoc researcher |
VPH institute and University of Liege |
Belgium |
|
Jeffrey Bajramovic |
Director 3Rs Centre Utrecht |
Utrecht University |
The Netherlands |
|
PD Dr.-Ing. Joachim Wiest |
Adjunct professor |
Technical University of Munich |
Germany |
|
Nicolas Bayer |
Master Student |
RPTU Kaiserslautern |
Germany |
ethically based funding!!! |
Christiane Spruck |
PhD student |
IUF |
Germany |
|
Florian Caiment |
Associate Professor |
Maastricht University |
The Netherlands |
|
Andreas Schiwy |
PostDoc, Teamleader |
Goethe University |
Germany |
The advancement of chemical defined media for culture of cells, replacement of animal derived products like fetal bovine serum as well as rat liver S9 with biotechnological alternatives. The development of physiological media to sustain cell lines that show similar reaction compared to the human body. |
Liliana Moreira Teixeira |
Assistant professor |
University of Twente |
The Netherlands |
|
busuqet |
ceo |
altertox |
Belgium |
|
John Grin |
Full professor in the governance of transitions |
University of Amsterdam |
The Netherlands |
|
Huub Schellekens |
Emeritus Professor |
Utrecht University |
The Netherlands |
|
Esther Wenzel |
COO |
Abcalis GmbH |
Germany |
|
Tamara Vanhaecke |
Professor |
Vrije Universiteit Brussel, Faculty of Medicine & Pharmacy |
Belgium |
|
Maria Tsamou |
Chief Scientific Officer |
ToxGenSolutions |
The Netherlands |
|
Emilio Benfenati |
Head of Department |
Istituto di Ricerche Farmacologiche Mario Negri |
Italy |
|
Wouter Dhert |
Professor and Scientific Director Innovation in Life Sciences |
Utrecht University |
The Netherlands |
|
Daniela Salvatori |
Professsor Anatomy and Physiology, Chairperson Animal-free Innovation Utrecht University |
Utrecht University |
The Netherlands |
Education (interprofessioanl education) and creation of a community able to go through the necessary changes |
Hanna Dusza |
Postdoctoral researcher |
Utrecht University |
The Netherlands |
|
Annalisa Gastaldello |
Project Officer |
European Commission |
Italy |
|
Konstantina |
PhD student |
VU Amsterdam |
The Netherlands |
Allocating funds to research aimed at developing in vitro methods modeling animal testing. |
Jakob (Jaap) Heringa |
Professor Bioinformatics |
Vrije Universiteit Amsterdam |
The Netherlands |
FAIR data infrastructure; Digital twin |
Jos Joore |
CEO |
Mimetas |
The Netherlands |
|
Victoria Marincheva |
Assist. Prof. |
University of Forestry Sofia |
Bulgaria |
|
Iliyan Manev |
Assos. Prof. in Immunology |
Faculty of Veterinary medicine, University of Forestry |
Bulgaria |
|
Eckhard von Keutz |
Consultant |
Independent |
Germany |
A concrete working plan which contains the deliverables and the associated timelines. Leadership and commitment are needed to execute on the roadmap. |
Jiayi Yang |
PhD candidate |
Utrecht University |
The Netherlands |
|
Silvia Scaglione |
Chief Scientist, President of React4life |
React4life |
Italy |
|
Kamile Jovaisaite |
Scientific Sales Representative |
STEMCELL Technologies |
The Netherlands |
|
Madalena Cipriano |
Senior Scientist |
University of Tübingen |
Germany |
|
Benoît Maisonneuve |
CSO |
NETRI |
France |
4 steps are necessary IMO: 1 - funding to develop and validate NAMs with clinical data, 2 - access to the clinical data (usually confidential), 3 - a regulatory framework to develop NAMs, and of course 4 - a legislative evolution of the European regulation (concerning drug developement etc) similar to what has been done in the USA and in India. |
Luiz Ladeira |
Postdoctoral researcher |
Liège Université |
Belgium |
|
Erwin L Roggen |
CEO |
ToxGenSolutions BV |
The Netherlands |
Wiilingness and confidence based on scientific data in stead of believe. |
Eva Bernet Kempers |
postdoctoral researcher |
University of Antwerp |
Belgium |
|
Line Mathiesen |
Associate Professor |
University of Copenhagen |
Denmark |
|
Ellen Fritsche |
Prof. |
IUF |
Germany |
|
Costanza Rovida |
Scientific Officer |
CAAT-Europe |
Germany |
|
Christian Maass |
Principal Scientist, Lead Digital Organ-on-Chip Platform |
esqLABS |
Germany |
Coordination with roadmap on standardization from CEN/CENELEC |
Timea Gandek |
Phd student |
University of Groningen |
The Netherlands |
|
Ramiro Jover |
Professor |
University of Valencia |
España |
|
Kathrin Herrmann |
Senior Associate |
Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) |
Germany |
|
Rafael Gozalbes |
CEO |
ProtoQSAR SL |
SPAIN |
|
Arno Gutleb |
Managing Director |
INVITROLIZE sarl |
Luxembourg |
|
Matthias Gossmann |
CEO |
innoVitro GmbH |
Germany |
|
Catarina Custódio |
CEO |
Metatissue |
Portugal |
|
Philippe Vanparys |
Retired scientist |
Consultant |
Belgium |
|
Marianna Norring |
Researcher |
University of Helsinki |
Finland |
|
Ariel Mörtengren |
Developer |
Masters degree in pharmacy |
Finland |
|
Hanna Vuorenpää |
Postdoctoral Research Fellow |
Tampere University |
Finland |
I would like to highlight the need for targeted funding for academic society with a clear message on investment on non-animal approaches across different disciplines. |
Jasper van Berkel |
COO |
Orgonex |
The Netherlands |
Organoids should replace animal testing |
Marta Tafalla |
Senior Lecturer |
Universitat Autònoma de Barcelona |
Spain |
|
Montserrat Escartin |
Full professor |
Universitat de Girona |
Spain |
|
Catia Faria |
Assistant Professor Moral Philosophy |
Complutense University of Madrid |
Spain |
|
Núria Almiron |
Professor |
Universitat Pompeu Fabra |
Spain |
|
jose ALbelda |
Profesor Titular de Universidad |
UPV |
España |
|
Cristian Moyano |
Postdoctoral researcher |
Universitat Autònoma de Barcelona |
Spain |
|
Vito D'Alessandro |
PhD Student |
Università del Salento |
Italy |
|
Lorena Rodríguez Mattalía |
Profesora titular de universidad |
Universidad Politécnica de Valencia |
España |
|
Asunción Herrera |
Profesora Titular Filosofía Moral |
Universidad de Oviedo |
España |
|
Paula Casal |
Professor |
ICREA and at Pompeu Fabra University |
Spain |
Start with banning any research which is not essential to tackle serious health problems, seek alternatives for the latter, and in the meantime maximally improve improve the conditions for animals, and stop killing the control group. To maximize adoptions of control group animals, ban their breeding for the companion animal industry. |
Sara Martín |
Senior Lecturer |
Universitat Autònoma de Barcelona |
Spain |
Obviously, the use of AI to simulate real-life experiments as approximately as possible |
Angélica Velasco |
Phd professor of moral philosophy |
University of Valladolid |
Spain |
|
Jorge Riechmann |
Profesor titular de Filosofía moral |
Departamento de Filosofía de la Universidad Autónoma de Madrid |
España |
|
Lucia Milec |
Project Manager |
Slovak Academy of Sciences |
Slovakia |
|
Laura Fernández |
Postdoctoral Researcher |
University of Barcelona / UPF-Centre for Animal Ethics |
Spain |
|
Pilar Medina-Bravo |
Senior Lecturer |
Universitat Pompeu Fabra |
Spain |
|
Marine Lercier |
Predoctoral Researcher and PhD Candidate in Animal Law |
Autonomous University of Barcelona |
Spain |
|
Miquel Rodrigo-Alsina |
Full Professor |
Universitat Pompeu Fabra |
Spain |
|
Priscila Alvarez Cueva |
Profesora contratada doctor |
Universidad Internacional de Valencia |
España |
|
Anna Wijen |
PhD student |
Maastricht University |
The Netherlands |
|
María Ruiz Carreras |
Lecturer |
Lund University |
Sweden |
|
Xavier Martinez Lacasa |
Medieval doctor |
Internal Medicine |
Spain |
|
Gemma Arca |
Neonatologa |
Hospital Clinic Barcelona |
Spain |
|
Paola Dolader |
Consultant |
Vall d’hebrob |
Spain |
|
LUIS FALCON |
PRESIDENT |
GNU SOLIDARIO |
SPAIN |
|
Nikolas Gaio |
CTO |
BIOND Solutions |
The Netherlands |
|
Kristie O’Neill |
Senior Researcher |
Radboud University |
The Netherlands |
|
Chrysafis Andreou |
Assistant Professor |
University of Cyprus |
Cyprus |
|
Giel Hendriks |
CEO |
Toxys |
The Netherlands |
Make funding available for SMEs to validate new methods. |
Hossein Eslami Amirabadi |
Managing Director |
AZAR Innovations |
The Netherlands |
|
Venetia Karamitsou |
Postdoc |
Sanofi |
Greece |
|
Peter J. Boogaard |
Professor of Environmental Health |
Wageningen University and Research |
Netherlands |
|
Marco Corvaro |
Technical Team Leader, Regulatory Toxicology |
Corteva Agriscience Italia S.r.l. |
Italy |
|
Niek Rijnveld |
CEO |
Optics11 Life |
Netherlands |
|
L. Cornips |
Senior-researcher |
NL-Lab (KNAW) & Maastricht University |
The Netherlands |
|
Sergio martínez mesón |
Researcher |
Instituto Catalán de Antropología |
Spain |
|
Surama Lázaro |
PhD student |
UNED |
Spain |
|
Simona Marzorati |
Project Manager |
NanoPhoria Srl |
Italy |
|
PJ Beers |
Senior Researcher |
Dutch Research Institute for Transitions |
The Netherlands |
|
Cyrille Krul |
Professor Innovative Testing in Life Sciences & Chemistry |
Utrecht University of Applied Sciences |
The Netherlands |
|
Iva Sovadinova |
Academic researcher |
Masaryk University, Faculty of Science, RECETOX |
Czechia |
|
Astrid Murumägi |
Senior Researcher |
University of Helsinki |
Finland |
|
Daniela Ungureanu |
Assoc. Prof. |
University of Helsinki |
Finland |
|
Delia Elena Diaconasu |
Researcher |
Alexandru Ioan Cuza University of Iasi |
Romania |
|
Harlan Barker |
PhD Student |
Tampere University |
Finland |
|
Alice Dini |
Doctoral Researcher |
University of Oulu |
Finland |
|
Carmen Madorrán Ayerra |
Assistant Professor |
Universidad Autónoma de Madrid |
Spain |
|
Anja Krippner-Heidenreich |
Senior Research Scientist |
Princess Maxima Centrum for Childhood Cancer |
The Netherlands |
|
Hubert Dirven |
Department Director Chemical toxicology |
Norwegian Institute of Public Health |
Norway |
Legislation for chemicals need to be revised |
Dr Brett A. Lidbury |
Associate Professor |
NCEPH - The Australian National University |
Australia |
We need a centre like ECVAAM to support non-animal innovation for biomedical research. |
Thomas Luechtefeld |
CEO |
ToxTrack Inc |
United States |
|
James Rathman |
Professor |
Ohio State University |
USA |
|
Yanitza Trosel |
Researcher |
Sunnybrook Research Institute |
Canada |
Start using mimic organ environments to test more basic system, then start increasing the complexity. |
David Pamies |
Research Associated |
Univeristy of Lausanne |
Switzerland |
|
Paula Brügger |
Professor coordinator of Ecological Justice Observatory |
Federal University of Santa Catarina |
Brazil |
|
Niraj Kumar |
Director |
M.s |
IND |
|
Pandora Pound |
Research Director |
Safer Medicines Trust |
UK |
|
Brigitte Franke-Bray |
Independent Consultant Pharmaceutical Medicine |
Freelance |
Switzerland |
|
Pelin Candarliogu |
Independent Consultant on the use of NAMS |
3D and 3Rs |
UK |
Standardisation guidelines followed with a qualification framework for specific context of use and independent test centres that will evaluate and qualify different NAMs for regulatory acceptance |
Dr Lilas Courtot |
Science Manager |
Animal Free Research UK |
United-Kingdom |
|
Francesca Pistollato |
Senior Strategist - Biomedical science |
HSI Europe |
Italy |
The transition towards human-relevant non-animal methods and models will help increase societal impact of funded research, in order to make scientific results really useful and translatable to human diseases and physiology. |
Manuela Cassotta |
Biologist Medical writer |
OSA (Oltre la Sperimentazione Animale) |
Italy |
|
Dr. Christiane Hohensee |
Subject specialist for Animal-free Research Methods |
Federal Association ip People for Animal Rights |
Germany |
|
Dr. Vera Marashi |
Senior Scientist |
Association Against Animal Factories (VEREIN GEGEN TIERFABRIKEN, VGT) |
Austria |
|
Kathy Archibald |
Chair |
Safer Medicines Trust |
UK |
|
Elma Omeragic |
Associate professor |
University of Sarajevo |
Bosnia and Herzegovina |
|
Dr. Michelle Sinclair |
Academic |
Stanford Medical School |
USA |